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SERPINA3 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant SERPINA3.

  • WB - SERPINA3 Antibody (monoclonal) (M01) AT3818a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (69.63 KDa) .
  • WB - SERPINA3 Antibody (monoclonal) (M01) AT3818a
    Western Blot analysis of SERPINA3 expression in transfected 293T cell line by SERPINA3 monoclonal antibody (M01), clone 1E6.

    Lane 1: SERPINA3 transfected lysate(47.7 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - SERPINA3 Antibody (monoclonal) (M01) AT3818a
    Immunoperoxidase of monoclonal antibody to SERPINA3 on formalin-fixed paraffin-embedded human ovary, clear cell carcinoma. [antibody concentration 1 ug/ml]
  • IP - SERPINA3 Antibody (monoclonal) (M01) AT3818a
    Immunoprecipitation of SERPINA3 transfected lysate using anti-SERPINA3 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SERPINA3 MaxPab rabbit polyclonal antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01011
Other Accession BC003559
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1E7
Calculated MW 47651 Da
Additional Information
Gene ID 12
Other Names Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, SERPINA3, AACT
Target/Specificity SERPINA3 (AAH03559, 25 a.a. ~ 423 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSERPINA3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. Is there an association of regulatory region polymorphism in the alpha-1-antichymotrypsin gene with sporadic Alzheimer's disease in the northern Han-Chinese population? Yu G, et al. J Clin Neurosci, 2010 Jun. PMID 20378355. Proteomic analysis of plasma from patients undergoing coronary artery bypass grafting reveals a protease/antiprotease imbalance in favor of the serpin alpha1-antichymotrypsin. Banfi C, et al. J Proteome Res, 2010 May 7. PMID 20302328. alpha(1)-Antichymotrypsin deficiency associated with liver cirrhosis. Ortega L, et al. Pediatr Int, 2010 Feb. PMID 20158662. Inhibition of heat- and chemical-induced aggregation of various proteins reveals chaperone-like activity of the acute-phase component and serine protease inhibitor human alpha(1)-antitrypsin. Zsila F. Biochem Biophys Res Commun, 2010 Mar 5. PMID 20117085.

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$ 315.00
Cat# AT3818a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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