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SERPINC1 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full length recombinant SERPINC1.

  • WB - SERPINC1 Antibody (monoclonal) (M02) AT3823a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (54.23 KDa) .
  • WB - SERPINC1 Antibody (monoclonal) (M02) AT3823a
    SERPINC1 monoclonal antibody (M02), clone 2B12. Western Blot analysis of SERPINC1 expression in human kidney.
  • WB - SERPINC1 Antibody (monoclonal) (M02) AT3823a
    Western Blot analysis of SERPINC1 expression in transfected 293T cell line by SERPINC1 monoclonal antibody (M02), clone 2B12.

    Lane 1: SERPINC1 transfected lysate(29.1 KDa).
    Lane 2: Non-transfected lysate.
  • E - SERPINC1 Antibody (monoclonal) (M02) AT3823a
    Detection limit for recombinant GST tagged SERPINC1 is 3 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01008
Other Accession BC022309
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 2B12
Calculated MW 52602 Da
Additional Information
Gene ID 462
Other Names Antithrombin-III, ATIII, Serpin C1, SERPINC1, AT3
Target/Specificity SERPINC1 (AAH22309.1, 1 a.a. ~ 259 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSERPINC1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.


Antithrombin Cambridge II(A384S) mutation frequency and antithrombin activity levels in 120 of deep venous thrombosis and 150 of cerebral infarction patients in a single center in Southern China. Zhang GS, et al. Blood Coagul Fibrinolysis, 2010 Sep. PMID 20683322.A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Romero R, et al. Am J Obstet Gynecol, 2010 Jul 29. PMID 20673868.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. Romero R, et al. Am J Obstet Gynecol, 2010 May. PMID 20452482.Polymorphisms in innate immunity genes and risk of childhood leukemia. Han S, et al. Hum Immunol, 2010 Jul. PMID 20438785.

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$ 315.00
Cat# AT3823a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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