SESN2 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full length recombinant SESN2.
|Application ||WB, IHC, IF, IP, E|
|Calculated MW||54494 Da|
|Other Names||Sestrin-2, Hi95, SESN2, SEST2|
|Target/Specificity||SESN2 (AAH13304.1, 1 a.a. ~ 480 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SESN2 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
1.The Inhibition of Autophagy Sensitises Colon Cancer Cells with Wild-Type p53 but Not Mutant p53 to Topotecan Treatment.Li DD, Sun T, Wu XQ, Chen SP, Deng R, Jiang S, Feng GK, Pan JX, Zhang XS, Zeng YX, Zhu XF.PLoS One. 2012;7(9):e45058. Epub 2012 Sep 14.2.Association of platelet-derived growth factor receptor accumulation with increased oxidative stress and cellular injury in sestrin 2 silenced human glioblastoma cells.Liu SY, Lee YJ, Lee TC.FEBS Lett. 2011 Apr 27. [Epub ahead of print]
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