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>   home   >   Products   >   Primary Antibodies   >   SF3B2 Antibody (monoclonal) (M01)   

SF3B2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SF3B2.

  • WB - SF3B2 Antibody (monoclonal) (M01) AT3838a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.68 KDa) .
  • WB - SF3B2 Antibody (monoclonal) (M01) AT3838a
    SF3B2 monoclonal antibody (M01), clone 5D2. Western Blot analysis of SF3B2 expression in PC-12 ( (Cat # AT3838a )
  • WB - SF3B2 Antibody (monoclonal) (M01) AT3838a
    SF3B2 monoclonal antibody (M01), clone 5D2 Western Blot analysis of SF3B2 expression in Hela S3 NE ( (Cat # AT3838a )
  • WB - SF3B2 Antibody (monoclonal) (M01) AT3838a
    SF3B2 monoclonal antibody (M01), clone 5D2. Western Blot analysis of SF3B2 expression in NIH/3T3 ( (Cat # AT3838a )
  • IHC - SF3B2 Antibody (monoclonal) (M01) AT3838a
    Immunoperoxidase of monoclonal antibody to SF3B2 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 6 ug/ml]
  • IF - SF3B2 Antibody (monoclonal) (M01) AT3838a
    Immunofluorescence of monoclonal antibody to SF3B2 on HeLa cell. [antibody concentration 60 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13435
Other Accession NM_006842
Reactivity Human, Mouse, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 5D2
Calculated MW 100228 Da
Additional Information
Gene ID 10992
Other Names Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145
Target/Specificity SF3B2 (NP_006833, 592 a.a. ~ 645 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSF3B2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.


Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo C, et al. Mol Cell, 2007 Jul 20. PMID 17643375.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.Human immunodeficiency virus type 1 Vpr induces G2 checkpoint activation by interacting with the splicing factor SAP145. Terada Y, et al. Mol Cell Biol, 2006 Nov. PMID 16923959.Induction of G2 arrest and binding to cyclophilin A are independent phenotypes of human immunodeficiency virus type 1 Vpr. Ardon O, et al. J Virol, 2006 Apr. PMID 16571786.

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$ 315.00
Cat# AT3838a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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