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SH2B Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SH2B.

  • WB - SH2B Antibody (monoclonal) (M01) AT3861a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - SH2B Antibody (monoclonal) (M01) AT3861a
    Western Blot analysis of SH2B1 expression in transfected 293T cell line by SH2B1 monoclonal antibody (M01), clone 2B9.

    Lane 1: SH2B1 transfected lysate(52.917 KDa).
    Lane 2: Non-transfected lysate.
  • IF - SH2B Antibody (monoclonal) (M01) AT3861a
    Immunofluorescence of monoclonal antibody to SH2B1 on HeLa cell . [antibody concentration 10 ug/ml]
  • E - SH2B Antibody (monoclonal) (M01) AT3861a
    Detection limit for recombinant GST tagged SH2B is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NRF2
Other Accession BC010704
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2B9
Calculated MW 79366 Da
Additional Information
Gene ID 25970
Other Names SH2B adapter protein 1, Pro-rich, PH and SH2 domain-containing signaling mediator, PSM, SH2 domain-containing protein 1B, SH2B1, KIAA1299, SH2B
Target/Specificity SH2B (AAH10704, 327 a.a. ~ 426 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSH2B Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described.


Evaluation of genetic susceptibility loci for obesity in Chinese women. Shi J, et al. Am J Epidemiol, 2010 Aug 1. PMID 20616199.Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. Fontaine-Bisson B, et al. Diabetologia, 2010 Oct. PMID 20571754.Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA. Holzapfel C, et al. Int J Obes (Lond), 2010 Apr 13. PMID 20386550.Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese. Ng MC, et al. J Clin Endocrinol Metab, 2010 May. PMID 20215397.Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study. Haupt A, et al. Obesity (Silver Spring), 2010 Jun. PMID 19910938.

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$ 315.00
Cat# AT3861a
(40 western blots)
Availability: 7-10 days
Bulk Size
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