SH3GLB1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant SH3GLB1.
|Application ||WB, IHC, E|
|Calculated MW||40796 Da|
|Other Names||Endophilin-B1, Bax-interacting factor 1, Bif-1, SH3 domain-containing GRB2-like protein B1, SH3GLB1, KIAA0491|
|Target/Specificity||SH3GLB1 (AAH07455, 1 a.a. ~ 365 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SH3GLB1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
GSK-3beta promotes cell survival by modulating Bif-1-dependent autophagy and cell death. Yang J, et al. J Cell Sci, 2010 Mar 15. PMID 20159967.Bax activates endophilin B1 oligomerization and lipid membrane vesiculation. Rostovtseva TK, et al. J Biol Chem, 2009 Dec 4. PMID 19805544.Somatic mutation of pro-cell death Bif-1 gene is rare in common human cancers. Kim MS, et al. APMIS, 2008 Oct. PMID 19132989.Bif-1 and Bax expression in cutaneous Merkel cell carcinoma. Schlauder SM, et al. J Cutan Pathol, 2009 Jan. PMID 19125733.Endophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large scale membrane morphological rearrangements. Etxebarria A, et al. J Biol Chem, 2009 Feb 13. PMID 19074440.
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