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SH3MD2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SH3MD2.

  • WB - SH3MD2 Antibody (monoclonal) (M01) AT3876a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - SH3MD2 Antibody (monoclonal) (M01) AT3876a
    SH3MD2 monoclonal antibody (M01), clone 3H3 Western Blot analysis of SH3MD2 expression in HeLa ( (Cat # AT3876a )
  • WB - SH3MD2 Antibody (monoclonal) (M01) AT3876a
    SH3MD2 monoclonal antibody (M01), clone 3H3. Western Blot analysis of SH3MD2 expression in PC-12 ( (Cat # AT3876a )
  • E - SH3MD2 Antibody (monoclonal) (M01) AT3876a
    Detection limit for recombinant GST tagged SH3MD2 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z6J0
Other Accession NM_020870
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3H3
Calculated MW 93129 Da
Additional Information
Gene ID 57630
Other Names E3 ubiquitin-protein ligase SH3RF1, 632-, Plenty of SH3s, Protein POSH, RING finger protein 142, SH3 domain-containing RING finger protein 1, SH3 multiple domains protein 2, SH3RF1, KIAA1494, POSH, RNF142, SH3MD2
Target/Specificity SH3MD2 (NP_065921, 790 a.a. ~ 888 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSH3MD2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.


1.Sh3rf2/POSHER promotes cell survival by RING-mediated proteasomal degradation of the JNK scaffold POSH.Wilhelm M, Kukekov NV, Schmit TL, Biagas KV, Sproul AA, Gire S, Maes ME, Xu Z, Greene LA.J Biol Chem. 2011 Nov 28.

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$ 315.00
Cat# AT3876a
(40 western blots)
Availability: 7-10 days
Bulk Size
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