SHC1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant SHC1.
|Application ||WB, IHC, IF, E|
|Calculated MW||62822 Da|
|Other Names||SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A, Src homology 2 domain-containing-transforming protein C1, SH2 domain protein C1, SHC1, SHC, SHCA|
|Target/Specificity||SHC1 (AAH33925, 171 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SHC1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells. Maj MC, et al. Biochem Biophys Res Commun, 2010 Aug 27. PMID 20637729.Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1. Mehlitz A, et al. J Cell Biol, 2010 Jul 12. PMID 20624904.Hyperglycemia-induced p66shc inhibits insulin-like growth factor I-dependent cell survival via impairment of Src kinase-mediated phosphoinositide-3 kinase/AKT activation in vascular smooth muscle cells. Xi G, et al. Endocrinology, 2010 Aug. PMID 20534722.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells. Xiao D, et al. Cancer Res, 2010 Apr 15. PMID 20354186.
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