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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SIGIRR Antibody (monoclonal) (M01)   

SIGIRR Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant SIGIRR.

  • WB - SIGIRR Antibody (monoclonal) (M01) AT3886a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (70.84 KDa) .
  • WB - SIGIRR Antibody (monoclonal) (M01) AT3886a
    SIGIRR monoclonal antibody (M01A), clone 3H8-2G3 Western Blot analysis of SIGIRR expression in HepG2 ( (Cat # AT3886a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6IA17
Other Accession BC003591
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgM kappa
Clone Names 3H8-2G3
Calculated MW 45679 Da
Additional Information
Gene ID 59307
Other Names Single Ig IL-1-related receptor, Single Ig IL-1R-related molecule, Single immunoglobulin domain-containing IL1R-related protein, Toll/interleukin-1 receptor 8, TIR8, SIGIRR
Target/Specificity SIGIRR (AAH03591, 1 a.a. ~ 410 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSIGIRR Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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SIGIRR/TIR-8 is an inhibitor of Toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis. Drexler SK, et al. Arthritis Rheum, 2010 Aug. PMID 20506350.Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. Mosbruger TL, et al. J Infect Dis, 2010 May 1. PMID 20331378.The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells. Khan MA, et al. J Immunol, 2010 Mar 1. PMID 20130217.TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Garlanda C, et al. Trends Immunol, 2009 Sep. PMID 19699681.Gene polymorphisms of Toll-like and related recognition receptors in relation to the vaginal carriage of Gardnerella vaginalis and Atopobium vaginae. Verstraelen H, et al. J Reprod Immunol, 2009 Jan. PMID 19200604.

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$ 315.00
Cat# AT3886a
(40 western blots)
Availability: 7-10 days
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