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SIGIRR Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant SIGIRR.
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- CITATIONS
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q6IA17 |
| Other Accession | BC003591 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgM kappa |
| Clone Names | 3H8-2G3 |
| Calculated MW | 45679 Da |
| Gene ID | 59307 |
|---|---|
| Other Names | Single Ig IL-1-related receptor, Single Ig IL-1R-related molecule, Single immunoglobulin domain-containing IL1R-related protein, Toll/interleukin-1 receptor 8, TIR8, SIGIRR |
| Target/Specificity | SIGIRR (AAH03591, 1 a.a. ~ 410 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SIGIRR Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
SIGIRR/TIR-8 is an inhibitor of Toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis. Drexler SK, et al. Arthritis Rheum, 2010 Aug. PMID 20506350.Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. Mosbruger TL, et al. J Infect Dis, 2010 May 1. PMID 20331378.The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells. Khan MA, et al. J Immunol, 2010 Mar 1. PMID 20130217.TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Garlanda C, et al. Trends Immunol, 2009 Sep. PMID 19699681.Gene polymorphisms of Toll-like and related recognition receptors in relation to the vaginal carriage of Gardnerella vaginalis and Atopobium vaginae. Verstraelen H, et al. J Reprod Immunol, 2009 Jan. PMID 19200604.
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