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SIX3 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SIX3.

  • WB - SIX3 Antibody (monoclonal) (M01) AT3893a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.6 KDa) .
  • WB - SIX3 Antibody (monoclonal) (M01) AT3893a
    SIX3 monoclonal antibody (M01), clone 3D12. Western Blot analysis of SIX3 expression in human thyroid(diffuse hyperplasia).
  • WB - SIX3 Antibody (monoclonal) (M01) AT3893a
    SIX3 monoclonal antibody (M01), clone 3D12 Western Blot analysis of SIX3 expression in 293 ( (Cat # AT3893a )
  • WB - SIX3 Antibody (monoclonal) (M01) AT3893a
    SIX3 monoclonal antibody (M01), clone 3D12. Western Blot analysis of SIX3 expression in MES-SA/Dx5 ( (Cat # AT3893a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95343
Other Accession NM_005413
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3D12
Calculated MW 35487 Da
Additional Information
Gene ID 6496
Other Names Homeobox protein SIX3, Sine oculis homeobox homolog 3, SIX3
Target/Specificity SIX3 (NP_005404, 273 a.a. ~ 332 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSIX3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2.


Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.Human variation in alcohol response is influenced by variation in neuronal signaling genes. Joslyn G, et al. Alcohol Clin Exp Res, 2010 May. PMID 20201926.Heterozygous mutations in SIX3 and SHH are associated with schizencephaly and further expand the clinical spectrum of holoprosencephaly. Hehr U, et al. Hum Genet, 2010 Mar. PMID 20157829.Mutational screening of 10 genes in Chinese patients with microphthalmia and/or coloboma. Zhang X, et al. Mol Vis, 2009 Dec 27. PMID 20057906.Absence of SIX3 mutations in patients with congenital hypopituitarism. Gaston-Massuet C, et al. Am J Med Genet A, 2009 Dec. PMID 19921650.

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$ 315.00
Cat# AT3893a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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