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SLC11A2 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT3900a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
SLC11A2 Antibody (monoclonal) (M01) - Product info | |
| Primary Accession | P49281 |
| Other Accession | NP_000608 |
| Reactivity | Human |
| Isotype | IgG2a Kappa |
| Clone Names | 4C6 |
| Calculated MW | 62266 Da |
SLC11A2 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 4891 | |
| Other Names DCT1, DMT1, NRAMP2solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | |
| Target/Specificity SLC11A2 (NP_000608, 1 a.a. ~ 66 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions SLC11A2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
SLC11A2 Antibody (monoclonal) (M01) - Related products
SLC11A2 Antibody (monoclonal) (M01) - Application data
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Immunoperoxidase of monoclonal antibody to SLC11A2 ( Cat # AT3900a ) on formalin-fixed paraffin-embedded human endometrium cancer. [antibody concentration 3ug/ml]
SLC11A2 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. Ucisik-Akkaya E, et al. Mol Hum Reprod, 2010 Oct. PMID 20587610.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1. Tabuchi M, et al. J Cell Sci, 2010 Mar 1. PMID 20164305.Interaction of calcium with the human divalent metal-ion transporter-1. Shawki A, et al. Biochem Biophys Res Commun, 2010 Mar 12. PMID 20152801.
