SLC25A11 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant SLC25A11.
|Application ||WB, IHC, E|
|Calculated MW||34062 Da|
|Other Names||Mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, Solute carrier family 25 member 11, SLC25A11, SLC20A4|
|Target/Specificity||SLC25A11 (AAH06508, 1 a.a. ~ 314 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SLC25A11 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summarized by Iacobazzi et al., 1992 [PubMed 1457818]).
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier. Kabe Y, et al. J Biol Chem, 2006 Oct 20. PMID 16920706.Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. Wang AG, et al. Biochem Biophys Res Commun, 2006 Jul 7. PMID 16712791.
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