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SLC9A1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SLC9A1.

  • WB - SLC9A1 Antibody (monoclonal) (M01) AT3932a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.41 KDa) .
  • IHC - SLC9A1 Antibody (monoclonal) (M01) AT3932a
    Immunoperoxidase of monoclonal antibody to SLC9A1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml]
  • E - SLC9A1 Antibody (monoclonal) (M01) AT3932a
    Detection limit for recombinant GST tagged SLC9A1 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P19634
Other Accession BC012121
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2F5
Calculated MW 90763 Da
Additional Information
Gene ID 6548
Other Names Sodium/hydrogen exchanger 1, APNH, Na(+)/H(+) antiporter, amiloride-sensitive, Na(+)/H(+) exchanger 1, NHE-1, Solute carrier family 9 member 1, SLC9A1, APNH1, NHE1
Target/Specificity SLC9A1 (AAH12121, 31 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSLC9A1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The Na+/H+ antiporter (SLC9A1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others (Mattei et al., 1988 [PubMed 2846238]).


Upregulation of Na+/H+ exchanger by the AMP-activated protein kinase. Rotte A, et al. Biochem Biophys Res Commun, 2010 Aug 6. PMID 20609358.NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance. Lauritzen G, et al. Exp Cell Res, 2010 Sep 10. PMID 20542029.Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human kidney proximal tubule cells. Holthouser KA, et al. Am J Physiol Renal Physiol, 2010 Jul. PMID 20427472.Inhibition of Na(+)/H(+) exchanger 1 by 5-(N-ethyl-N-isopropyl) amiloride reduces hypoxia-induced hepatocellular carcinoma invasion and motility. Yang X, et al. Cancer Lett, 2010 Sep 28. PMID 20338684.Activation of Na+/H+ exchanger 1 by neurotensin signaling in pancreatic cancer cell lines. Olszewski U, et al. Biochem Biophys Res Commun, 2010 Mar 12. PMID 20138826.

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$ 315.00
Cat# AT3932a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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