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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SMAD7 Antibody (monoclonal) (M09)   

SMAD7 Antibody (monoclonal) (M09)

Mouse monoclonal antibody raised against a partial recombinant SMAD7.

  • WB - SMAD7 Antibody (monoclonal) (M09) AT3949a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.85 KDa) .
  • IHC - SMAD7 Antibody (monoclonal) (M09) AT3949a
    Immunoperoxidase of monoclonal antibody to SMAD7 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
  • E - SMAD7 Antibody (monoclonal) (M09) AT3949a
    Detection limit for recombinant GST tagged SMAD7 is 0.3 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15105
Other Accession NM_005904
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1G10
Calculated MW 46426 Da
Additional Information
Gene ID 4092
Other Names Mothers against decapentaplegic homolog 7, MAD homolog 7, Mothers against DPP homolog 7, Mothers against decapentaplegic homolog 8, MAD homolog 8, Mothers against DPP homolog 8, SMAD family member 7, SMAD 7, Smad7, hSMAD7, SMAD7, MADH7, MADH8
Target/Specificity SMAD7 (NP_005895, 160 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSMAD7 Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.


1.Aberrant expression in multiple components of the transforming growth factor-?]1-induced Smad signaling pathway during 7,12-dimethylbenz[a]anthracene-induced hamster buccal-pouch squamous-cell carcinogenesis.Chen YK, Yang SH, Huang AH, Hsue SS, Lin LM.Oral Oncol. 2011 Feb 26. [Epub ahead of print]

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$ 315.00
Cat# AT3949a
(40 western blots)
Availability: 7-10 days
Bulk Size
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