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SNCG Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant SNCG.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O76070 |
| Other Accession | BC014098 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2C3 |
| Calculated MW | 13331 Da |
| Gene ID | 6623 |
|---|---|
| Other Names | Gamma-synuclein, Breast cancer-specific gene 1 protein, Persyn, Synoretin, SR, SNCG, BCSG1, PERSYN, PRSN |
| Target/Specificity | SNCG (AAH14098, 21 a.a. ~ 127 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SNCG Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development.
References
Association of alpha-, beta-, and gamma-Synuclein with diffuse lewy body disease. Nishioka K, et al. Arch Neurol, 2010 Aug. PMID 20697047.Expression of alpha-, beta- and gamma-synuclein in colorectal cancer, and potential clinical significance in progression of the disease. Ye Q, et al. Oncol Rep, 2010 Feb. PMID 20043104.Expression of gamma-synuclein in colorectal cancer tissues and its role on colorectal cancer cell line HCT116. Ye Q, et al. World J Gastroenterol, 2009 Oct 28. PMID 19859996.Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis. Hu H, et al. Clin Cancer Res, 2009 Sep 1. PMID 19706805.Partial regulation of serotonin transporter function by gamma-synuclein. Wersinger C, et al. Neurosci Lett, 2009 Apr 10. PMID 19429025.
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