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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SOCS3 Antibody (monoclonal) (M02)   

SOCS3 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full length recombinant SOCS3.

  • IHC - SOCS3 Antibody (monoclonal) (M02) AT3988a
    Immunoperoxidase of monoclonal antibody to SOCS3 on formalin-fixed paraffin-embedded human colon. [antibody concentration 1.5 ug/ml]
  • IF - SOCS3 Antibody (monoclonal) (M02) AT3988a
    Immunofluorescence of monoclonal antibody to SOCS3 on HeLa cell . [antibody concentration 10 ug/ml]
  • E - SOCS3 Antibody (monoclonal) (M02) AT3988a
    Detection limit for recombinant GST tagged SOCS3 is approximately 3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14543
Other Accession BC060858
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 1E5
Calculated MW 24770 Da
Additional Information
Gene ID 9021
Other Names Suppressor of cytokine signaling 3, SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SSI-3, SOCS3, CIS3, SSI3
Target/Specificity SOCS3 (AAH60858, 1 a.a. ~ 225 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSOCS3 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.


1.Epigenetic silencing of SOCS3 identifies a subset of prostate cancer with an aggressive behavior.Pierconti F, Martini M, Pinto F, Cenci T, Capodimonti S, Calarco A, Bassi PF, Larocca LM.Prostate. 2010 Aug 17. [Epub ahead of print]

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$ 315.00
Cat# AT3988a
(40 western blots)
Availability: 7-10 days
Bulk Size
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