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SP7 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SP7.

  • WB - SP7 Antibody (monoclonal) (M01) AT4011a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.1 KDa) .
  • IF - SP7 Antibody (monoclonal) (M01) AT4011a
    Immunofluorescence of monoclonal antibody to SP7 on HeLa cell . [antibody concentration 10 ug/ml]
  • E - SP7 Antibody (monoclonal) (M01) AT4011a
    Detection limit for recombinant GST tagged SP7 is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TDD2
Other Accession NM_152860
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2G6
Calculated MW 44994 Da
Additional Information
Gene ID 121340
Other Names Transcription factor Sp7, Zinc finger protein osterix, SP7, OSX
Target/Specificity SP7 (NP_690599, 87 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSP7 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.


Identification of a frameshift mutation in Osterix in a patient with recessive osteogenesis imperfecta. Lapunzina P, et al. Am J Hum Genet, 2010 Jul 9. PMID 20579626.Replication of previous genome-wide association studies of bone mineral density in premenopausal American women. Ichikawa S, et al. J Bone Miner Res, 2010 Aug. PMID 20200978.Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase. Sinha KM, et al. EMBO J, 2010 Jan 6. PMID 19927124.Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Rivadeneira F, et al. Nat Genet, 2009 Nov. PMID 19801982.High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Yerges LM, et al. J Bone Miner Res, 2009 Dec. PMID 19453261.

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$ 315.00
Cat# AT4011a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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