SPARC Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a full length recombinant SPARC.
|Application ||WB, E|
|Calculated MW||34632 Da|
|Other Names||SPARC, Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine, SPARC, ON|
|Target/Specificity||SPARC (AAH04974.1, 1 a.a. ~ 303 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SPARC Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Secreted protein acidic and rich in cysteine/osteonectin/BM40, or SPARC, is a matrix-associated protein that elicits changes in cell shape, inhibits cell-cycle progression, and influences the synthesis of extracellular matrix (ECM) (Bradshaw et al., 2003 [PubMed 12721366]).
1.The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses.Piconese S, Costanza M, Tripodo C, Sangaletti S, Musio S, Pittoni P, Poliani PL, Burocchi A, Passafaro AL, Gorzanelli A, Vitali C, Chiodoni C, Barnaba V, Pedotti R, Colombo MP.J Autoimmun. 2011 Sep 28.
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