SPRR3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant SPRR3.
|Application ||WB, IHC, E|
|Calculated MW||18154 Da|
|Other Names||Small proline-rich protein 3, 22 kDa pancornulin, Cornifin beta, Esophagin, SPRR3, SPRC|
|Target/Specificity||SPRR3 (AAH17802, 1 a.a. ~ 161 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SPRR3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Characterization of two isoforms of human SPRR3 from saliva of preterm human newborn and autoptic fetal oral mucosa, parotid and submandibular gland samples. Manconi B, et al. Biochem Biophys Res Commun, 2010 Jul 30. PMID 20599699.Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress. Pyle AL, et al. Cardiovasc Pathol, 2010 Mar-Apr. PMID 19211270.Regulation of the atheroma-enriched protein, SPRR3, in vascular smooth muscle cells through cyclic strain is dependent on integrin alpha1beta1/collagen interaction. Pyle AL, et al. Am J Pathol, 2008 Nov. PMID 18832573.Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families. Kainu K, et al. Exp Dermatol, 2009 Feb. PMID 18643845.Exogenous expression of Esophagin/SPRR3 attenuates the tumorigenicity of esophageal squamous cell carcinoma cells via promoting apoptosis. Zhang Y, et al. Int J Cancer, 2008 Jan 15. PMID 17935133.
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