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STAT3 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant STAT3.

  • WB - STAT3 Antibody (monoclonal) (M02) AT4062a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - STAT3 Antibody (monoclonal) (M02) AT4062a
    STAT3 monoclonal antibody (M02), clone 4D6 Western Blot analysis of STAT3 expression in HeLa ( (Cat # AT4062a )
  • IF - STAT3 Antibody (monoclonal) (M02) AT4062a
    Immunofluorescence of monoclonal antibody to STAT3 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - STAT3 Antibody (monoclonal) (M02) AT4062a
    Detection limit for recombinant GST tagged STAT3 is approximately 0.1ng/ml as a capture antibody.
  •  - STAT3 Antibody (monoclonal) (M02) AT4062a
    Proximity Ligation Analysis of protein-protein interactions between NFKB1 and STAT3 HeLa cells were stained with anti-NFKB1 rabbit purified polyclonal 1:1200 and anti-STAT3 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P40763
Other Accession NM_003150
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4D6
Calculated MW 88068 Da
Additional Information
Gene ID 6774
Other Names Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3, APRF
Target/Specificity STAT3 (NP_003141, 670 a.a. ~ 769 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSTAT3 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.


1.Acetylation Directs Survivin Nuclear Localization to Repress STAT3 Oncogenic Activity.Wang H, Holloway MP, Ma L, Cooper ZA, Riolo M, Samkari A, Elenitoba-Johnson KS, Chin YE, Altura RA.J Biol Chem. 2010 Nov 12;285(46):36129-37. Epub 2010 Sep 8.

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$ 315.00
Cat# AT4062a
(40 western blots)
Availability: 7-10 days
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