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SYNJ1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SYNJ1.

     
  • WB - SYNJ1 Antibody (monoclonal) (M01) AT4123a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
    detail
  • WB - SYNJ1 Antibody (monoclonal) (M01) AT4123a
    SYNJ1 monoclonal antibody (M01), clone 1A2 Western Blot analysis of SYNJ1 expression in Hela S3 NE ( (Cat # AT4123a )
    detail
  • E - SYNJ1 Antibody (monoclonal) (M01) AT4123a
    Detection limit for recombinant GST tagged SYNJ1 is approximately 0.3ng/ml as a capture antibody.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O43426
Other Accession NM_003895
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1A2
Calculated MW 173103 Da
Additional Information
Gene ID 8867
Other Names Synaptojanin-1, Synaptic inositol 1, 5-trisphosphate 5-phosphatase 1, SYNJ1, KIAA0910
Target/Specificity SYNJ1 (NP_003886, 1474 a.a. ~ 1573 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSYNJ1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

Synaptojanin 1 is a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking.

References

Alternative splicing affecting the SH3A domain controls the binding properties of intersectin 1 in neurons. Tsyba L, et al. Biochem Biophys Res Commun, 2008 Aug 8. PMID 18539136.Root hair defective4 encodes a phosphatidylinositol-4-phosphate phosphatase required for proper root hair development in Arabidopsis thaliana. Thole JM, et al. Plant Cell, 2008 Feb. PMID 18281508.Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Perera RM, et al. Proc Natl Acad Sci U S A, 2006 Dec 19. PMID 17158794.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.SNX9 as an adaptor for linking synaptojanin-1 to the Cdc42 effector ACK1. Yeow-Fong L, et al. FEBS Lett, 2005 Sep 12. PMID 16137687.

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$ 350.00
Cat# AT4123a
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