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TAC3 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant TAC3.

  • WB - TAC3 Antibody (monoclonal) (M01) AT4132a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.07 KDa) .
  • E - TAC3 Antibody (monoclonal) (M01) AT4132a
    Detection limit for recombinant GST tagged TAC3 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UHF0
Other Accession BC032145
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 2D7
Calculated MW 13438 Da
Additional Information
Gene ID 6866
Other Names Tachykinin-3, ZNEUROK1, Neurokinin-B, NKB, Neuromedin-K, TAC3, NKNB
Target/Specificity TAC3 (AAH32145, 17 a.a. ~ 121 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTAC3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants.


Common variants of the neuropeptide expressing tachykinin genes and susceptibility to asthma: a case-control study. Klassert TE, et al. J Neuroimmunol, 2010 Oct 8. PMID 20580442.Neurokinin B and its receptor in hypogonadotropic hypogonadism. Semple RK, et al. Front Horm Res, 2010. PMID 20389091.TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood. Gianetti E, et al. J Clin Endocrinol Metab, 2010 Jun. PMID 20332248.TAC3 and TACR3 defects cause hypothalamic congenital hypogonadotropic hypogonadism in humans. Young J, et al. J Clin Endocrinol Metab, 2010 May. PMID 20194706.Neurokinin B signaling in puberty: human and animal studies. Topaloglu AK. Mol Cell Endocrinol, 2010 Aug 5. PMID 20176081.

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$ 315.00
Cat# AT4132a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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