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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   TBX5 Antibody (monoclonal) (M01)   

TBX5 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant TBX5.

  • WB - TBX5 Antibody (monoclonal) (M01) AT4171a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (38.61 KDa) .
  • WB - TBX5 Antibody (monoclonal) (M01) AT4171a
    Western Blot analysis of TBX5 expression in transfected 293T cell line by TBX5 monoclonal antibody (M01), clone 1G10.

    Lane 1: TBX5 transfected lysate(57.7 KDa).
    Lane 2: Non-transfected lysate.
  • E - TBX5 Antibody (monoclonal) (M01) AT4171a
    Detection limit for recombinant GST tagged TBX5 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99593
Other Accession BC027942
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1G10
Calculated MW 57711 Da
Additional Information
Gene ID 6910
Other Names T-box transcription factor TBX5, T-box protein 5, TBX5
Target/Specificity TBX5 (AAH27942, 402 a.a. ~ 518 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTBX5 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.


1.Holt-Oram syndrome with intermediate atrioventricular canal defect, and aortic coarctation: Functional characterization of a de novo TBX5 mutation.Baban A, Pitto L, Pulignani S, Cresci M, Mariani L, Gambacciani C, Digilio MC, Pongiglione G, Albanese SAm J Med Genet A. 2014 Jun;164(6):1419-24. doi: 10.1002/ajmg.a.36459. Epub 2014 Mar 24.2.Directing cardiomyogenic differentiation of human pluripotent stem cells by plasmid-based transient overexpression of cardiac transcription factors.Hartung S, Schwanke K, Haase A, David R, Franz WM, Martin U, Zweigerdt RStem Cells Dev. 2013 Apr 1;22(7):1112-25. doi: 10.1089/scd.2012.0351. Epub 2013 Jan 18.3.Physical interaction between TBX5 and MEF2C is required for early heart development.Ghosh TK, Song FF, Packham EA, Buxton S, Robinson TE, Ronksley J, Self T, Bonser AJ, Brook JD.Mol Cell Biol. 2009 Apr;29(8):2205-18. Epub 2009 Feb 9.

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$ 315.00
Cat# AT4171a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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