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TCF7L2 Antibody (monoclonal) (M06)

Mouse monoclonal antibody raised against a partial recombinant TCF7L2.

  • WB - TCF7L2 Antibody (monoclonal) (M06) AT4192a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.51 KDa) .
  • WB - TCF7L2 Antibody (monoclonal) (M06) AT4192a
    TCF7L2 monoclonal antibody (M06), clone 3A4 Western Blot analysis of TCF7L2 expression in K-562 ( (Cat # AT4192a )
  • IHC - TCF7L2 Antibody (monoclonal) (M06) AT4192a
    Immunoperoxidase of monoclonal antibody to TCF7L2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]
  • IF - TCF7L2 Antibody (monoclonal) (M06) AT4192a
    Immunofluorescence of monoclonal antibody to TCF7L2 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - TCF7L2 Antibody (monoclonal) (M06) AT4192a
    Detection limit for recombinant GST tagged TCF7L2 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQB0
Other Accession NM_030756
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 3A4
Calculated MW 67919 Da
Additional Information
Gene ID 6934
Other Names Transcription factor 7-like 2, HMG box transcription factor 4, T-cell-specific transcription factor 4, T-cell factor 4, TCF-4, hTCF-4, TCF7L2, TCF4
Target/Specificity TCF7L2 (NP_110383, 490 a.a. ~ 596 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTCF7L2 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes.


Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion. Heni M, et al. Diabetes, 2010 Aug 29. PMID 20802253.Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study. Kucharska-Newton AM, et al. J Obes, 2010. PMID 20798759.Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: common genetic variants in GCK and TCF7L2 are associated with fasting and post-challenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes from the International Association of Diabetes and Pregnancy Study Groups. Freathy RM, et al. Diabetes, 2010 Aug 3. PMID 20682688.The balance of TCF7L2 variants with differential activities in Wnt-signaling is regulated by lithium in a GSK3beta-independent manner. Struewing I, et al. Biochem Biophys Res Commun, 2010 Aug 20. PMID 20654575.Potential role of TCF7L2 gene variants on cardiac sympathetic/parasympathetic activity. Boccardi V, et al. Eur J Hum Genet, 2010 Jul 21. PMID 20648057.

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$ 315.00
Cat# AT4192a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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