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TDO2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant TDO2.

  • E - TDO2 Antibody (monoclonal) (M01) AT4199a
    Detection limit for recombinant GST tagged TDO2 is approximately 10ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P48775
Other Accession NM_005651
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1C8
Calculated MW 47872 Da
Additional Information
Gene ID 6999
Other Names Tryptophan 2, 3-dioxygenase {ECO:0000255|HAMAP-Rule:MF_03020}, TDO {ECO:0000255|HAMAP-Rule:MF_03020}, 1131111 {ECO:0000255|HAMAP-Rule:MF_03020}, Tryptamin 2, 3-dioxygenase {ECO:0000255|HAMAP-Rule:MF_03020}, Tryptophan oxygenase {ECO:0000255|HAMAP-Rule:MF_03020}, TO {ECO:0000255|HAMAP-Rule:MF_03020}, TRPO {ECO:0000255|HAMAP-Rule:MF_03020}, Tryptophan pyrrolase {ECO:0000255|HAMAP-Rule:MF_03020}, Tryptophanase {ECO:0000255|HAMAP-Rule:MF_03020}, TDO2 {ECO:0000255|HAMAP-Rule:MF_03020}, TDO
Target/Specificity TDO2 (NP_005642, 307 a.a. ~ 405 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTDO2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Tryptophan 2,3-dioxygenase (EC plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.


First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children. Roeske D, et al. Mol Psychiatry, 2009 Sep 29. PMID 19786962.Antimicrobial and immunoregulatory properties of human tryptophan 2,3-dioxygenase. Schmidt SK, et al. Eur J Immunol, 2009 Oct. PMID 19637229.Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder. Miller CL, et al. Schizophr Res, 2009 Sep. PMID 19502010.Cooperative binding of L-trp to human tryptophan 2,3-dioxygenase: resonance Raman spectroscopic analysis. Fukumura E, et al. J Biochem, 2009 Apr. PMID 19218188.A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase. Basran J, et al. Biochemistry, 2008 Apr 22. PMID 18370401.

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$ 315.00
Cat# AT4199a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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