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TFAP2B Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant TFAP2B.

  • WB - TFAP2B Antibody (monoclonal) (M02) AT4212a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - TFAP2B Antibody (monoclonal) (M02) AT4212a
    Western Blot analysis of TFAP2B expression in transfected 293T cell line by TFAP2B monoclonal antibody (M02), clone 2F6.

    Lane 1: TFAP2B transfected lysate(50.474 KDa).
    Lane 2: Non-transfected lysate.
  • IF - TFAP2B Antibody (monoclonal) (M02) AT4212a
    Immunofluorescence of monoclonal antibody to TFAP2B on HeLa cell . [antibody concentration 10 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92481
Other Accession NM_003221
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2F6
Calculated MW 50474 Da
Additional Information
Gene ID 7021
Other Names Transcription factor AP-2-beta, AP2-beta, Activating enhancer-binding protein 2-beta, TFAP2B
Target/Specificity TFAP2B (NP_003212, 73 a.a. ~ 182 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTFAP2B Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.


Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population. Hotta K, et al. J Hum Genet, 2010 Aug 12. PMID 20703240.Transcription factor AP2 beta involved in severe female alcoholism. Nordquist N, et al. Brain Res, 2009 Dec 11. PMID 19778525.Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. Lindgren CM, et al. PLoS Genet, 2009 Jun. PMID 19557161.Determination of genetic predisposition to patent ductus arteriosus in preterm infants. Dagle JM, et al. Pediatrics, 2009 Apr. PMID 19336370.The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents. Nordquist N, et al. Obesity (Silver Spring), 2009 Sep. PMID 19325541.

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$ 315.00
Cat# AT4212a
(40 western blots)
Availability: 7-10 days
Bulk Size
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