TIPIN Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant TIPIN.
|Application ||WB, IF, E|
|Calculated MW||34555 Da|
|Other Names||TIMELESS-interacting protein, TIPIN|
|Target/Specificity||TIPIN (AAH00870, 1 a.a. ~ 301 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||TIPIN Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress. Kemp MG, et al. J Biol Chem, 2010 May 28. PMID 20233725.Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance. Utge SJ, et al. PLoS One, 2010 Feb 18. PMID 20174623.Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion. Leman AR, et al. J Cell Sci, 2010 Mar 1. PMID 20124417.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Unsal-Ka?maz K, et al. Mol Cell Biol, 2007 Apr. PMID 17296725.
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