TNFRSF21 Antibody (monoclonal) (M08)
Mouse monoclonal antibody raised against a full length recombinant TNFRSF21.
|Calculated MW||71845 Da|
|Other Names||Tumor necrosis factor receptor superfamily member 21, Death receptor 6, CD358, TNFRSF21, DR6|
|Target/Specificity||TNFRSF21 (AAH05192.1, 1 a.a. ~ 124 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||TNFRSF21 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.|
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq]
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