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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TNFRSF7 Antibody (monoclonal) (M01)   

TNFRSF7 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant TNFRSF7.

  • WB - TNFRSF7 Antibody (monoclonal) (M01) AT4282a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (54.34 KDa) .
  • WB - TNFRSF7 Antibody (monoclonal) (M01) AT4282a
    TNFRSF7 monoclonal antibody (M01), clone 1E2-A3 Western Blot analysis of TNFRSF7 expression in Jurkat ( (Cat # AT4282a )
  • WB - TNFRSF7 Antibody (monoclonal) (M01) AT4282a
    Western Blot analysis of TNFRSF7 expression in transfected 293T cell line by TNFRSF7 monoclonal antibody (M01), clone 1E2-A3.

    Lane 1: TNFRSF7 transfected lysate(29.2 KDa).
    Lane 2: Non-transfected lysate.
  • E - TNFRSF7 Antibody (monoclonal) (M01) AT4282a
    Detection limit for recombinant GST tagged CD27 is 0.3 ng/ml as a capture antibody.
  • WB - TNFRSF7 Antibody (monoclonal) (M01) AT4282a
    Western blot analysis of TNFRSF7 over-expressed 293 cell line, cotransfected with TNFRSF7 Validated Chimera RNAi ( (Cat # AT4282a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P26842
Other Accession BC012160
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b kappa
Clone Names 1E2-A3
Calculated MW 29137 Da
Additional Information
Gene ID 939
Other Names CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7
Target/Specificity TNFRSF7 (AAH12160, 1 a.a. ~ 260 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTNFRSF7 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.


Possible recruitment of peripheral blood CXCR3+ CD27+ CD19+ B cells to the liver of chronic hepatitis C patients. Mizuochi T, et al. J Interferon Cytokine Res, 2010 Apr. PMID 20377416.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation. Arimoto-Miyamoto K, et al. Immunology, 2010 May. PMID 20201989.CD40-activated B cells from patients with systemic lupus erythematosus can be modulated by therapeutic immunoglobulins in vitro. N?ron S, et al. Arch Immunol Ther Exp (Warsz), 2009 Nov-Dec. PMID 19866343.Defining origins of malignant B cells: a new circulating normal human IgM(+)D(+) B-cell subset lacking CD27 expression and displaying somatically mutated IGHV genes as a relevant memory population. Weston-Bell N, et al. Leukemia, 2009 Nov. PMID 19776762.

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$ 315.00
Cat# AT4282a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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