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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TOPORS Antibody (monoclonal) (M01)   

TOPORS Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant TOPORS.

  • WB - TOPORS Antibody (monoclonal) (M01) AT4308a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.62 KDa) .
  • IHC - TOPORS Antibody (monoclonal) (M01) AT4308a
    Immunoperoxidase of monoclonal antibody to TOPORS on formalin-fixed paraffin-embedded human lung, adenosquamous cell carcinoma. [antibody concentration 3 ug/ml]
  • IF - TOPORS Antibody (monoclonal) (M01) AT4308a
    Immunofluorescence of monoclonal antibody to TOPORS on HeLa cell. [antibody concentration 10 ug/ml]
  • E - TOPORS Antibody (monoclonal) (M01) AT4308a
    Detection limit for recombinant GST tagged TOPORS is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NS56
Other Accession NM_005802
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 5G11
Calculated MW 119198 Da
Additional Information
Gene ID 10210
Other Names E3 ubiquitin-protein ligase Topors, 632-, SUMO1-protein E3 ligase Topors, Topoisomerase I-binding RING finger protein, Topoisomerase I-binding arginine/serine-rich protein, Tumor suppressor p53-binding protein 3, p53-binding protein 3, p53BP3, TOPORS, LUN, TP53BPL
Target/Specificity TOPORS (NP_005793, 98 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTOPORS Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.


1.Mitotic Phosphorylation Stimulates DNA Relaxation Activity of Human Topoisomerase I.Hackbarth JS, Galvez-Peralta M, Dai NT, Loegering DA, Peterson KL, Meng XW, Karnitz LM, Kaufmann SH.J Biol Chem. 2008 Jun 13;283(24):16711-22. Epub 2008 Apr 11.

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$ 315.00
Cat# AT4308a
(40 western blots)
Availability: 7-10 days
Bulk Size
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