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TPI1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant TPI1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P60174 |
| Other Accession | BC007086 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1D10-2E2 |
| Calculated MW | 26669 Da |
| Gene ID | 7167 |
|---|---|
| Other Names | Triosephosphate isomerase, TIM, Triose-phosphate isomerase, TPI1, TPI |
| Target/Specificity | TPI1 (AAH07086.1, 1 a.a. ~ 249 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | TPI1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
References
1.Impact of cisplatin administration on protein expression levels in renal cell carcinoma: A proteomic analysis.Vasko R, Mueller GA, von Jaschke AK, Asif AR, Dihazi H.Eur J Pharmacol. 2011 Sep 8.2.Proteomic Analysis of Butyrate Effects and Loss of Butyrate Sensitivity in HT29 Colorectal Cancer Cells.Fung KY, Lewanowitsch T, Henderson ST, Priebe I, Hoffmann P, Lockett T, Head R, Cosgrove LJ.J Proteome Res. 2009 Mar;8(3):1220-7.3.Proteome of human T lymphocytes with treatment of cyclosporine and polysaccharopeptide: Analysis of significant proteins that manipulate T cells proliferation and immunosuppression.Lee CL, Jiang PP, Sit WH, Wan JM.Int Immunopharmacol. 2007 Oct;7(10):1311-24. Epub 2007 Jun 19.
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