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TRAF4 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant TRAF4.

  • WB - TRAF4 Antibody (monoclonal) (M01) AT4331a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - TRAF4 Antibody (monoclonal) (M01) AT4331a
    Western Blot analysis of TRAF4 expression in transfected 293T cell line by TRAF4 monoclonal antibody (M01), clone 3F6.

    Lane 1: TRAF4 transfected lysate(53.5 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - TRAF4 Antibody (monoclonal) (M01) AT4331a
    Immunoperoxidase of monoclonal antibody to TRAF4 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]
  • E - TRAF4 Antibody (monoclonal) (M01) AT4331a
    Detection limit for recombinant GST tagged TRAF4 is 3 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BUZ4
Other Accession BC001769
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3F6
Calculated MW 53543 Da
Additional Information
Gene ID 9618
Other Names TNF receptor-associated factor 4, Cysteine-rich domain associated with RING and Traf domains protein 1, Metastatic lymph node gene 62 protein, MLN 62, RING finger protein 83, TRAF4, CART1, MLN62, RNF83
Target/Specificity TRAF4 (AAH01769, 371 a.a. ~ 470 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTRAF4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.


New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment. Segat L, et al. Vaccine, 2010 Mar 2. PMID 20056178.Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation. Li S, et al. Mol Cell Biochem, 2010 May. PMID 19937093.Tumor necrosis factor receptor-associated factor 4 is a dynamic tight junction-related shuttle protein involved in epithelium homeostasis. K?dinger V, et al. PLoS One, 2008. PMID 18953416.The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis. Albers HM, et al. Ann Rheum Dis, 2008 Nov. PMID 18593758.

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$ 315.00
Cat# AT4331a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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