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TRAPPC2 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT4333a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
TRAPPC2 Antibody (monoclonal) (M01) - Product info | |
| Application | WB
|
| Primary Accession | P0DI81 |
| Reactivity | Human |
| Isotype | IgG2b kappa |
| Clone Names | 20000000000 |
| Calculated MW | 16445 Da |
TRAPPC2 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 6399 | |
| Other Names MIP2A, SEDL, SEDT, TRS20, ZNF547L, hYP38334trafficking protein particle complex 2 | |
| Target/Specificity TRAPPC2 (AAH16915, 1 a.a. ~ 141 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions TRAPPC2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
TRAPPC2 Antibody (monoclonal) (M01) - Related products
TRAPPC2 Antibody (monoclonal) (M01) - Application data
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TRAPPC2 monoclonal antibody (M01), clone 2E10 Western Blot analysis of TRAPPC2 expression in Hela ( Cat # L013V1 ).
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Detection limit for recombinant GST tagged TRAPPC2 is approximately 0.3ng/ml as a capture antibody.
TRAPPC2 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene.
REFERENCES
SEDLIN forms homodimers: characterisation of SEDLIN mutations and their interactions with transcription factors MBP1, PITX1 and SF1. Jeyabalan J, et al. PLoS One, 2010 May 14. PMID 20498720.Interaction of Sedlin with PAM14. Liu X, et al. J Cell Biochem, 2010 Apr 15. PMID 20108251.A novel insertion mutation in the SEDL gene results in X-linked spondyloepiphyseal dysplasia tarda in a large Chinese pedigree. Xia XY, et al. Clin Chim Acta, 2009 Dec. PMID 19766614.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.A novel RNA-splicing mutation in TRAPPC2 gene causing x-linked spondyloepiphyseal dysplasia tarda in a large Chinese family. Guo H, et al. J Genet, 2009 Apr. PMID 19417549.
