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TRIM68 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT4362a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
TRIM68 Antibody (monoclonal) (M01) - Product info | |
| Primary Accession | Q6AZZ1 |
| Other Accession | NP_060543 |
| Reactivity | Human |
| Concentration | 1 mg/ml |
| Isotype | IgG2a Kappa |
| Clone Names | 5G2 |
| Calculated MW | 56259 Da |
TRIM68 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 55128 | |
| Other Names FLJ10369, RNF137, SS56tripartite motif-containing 68 | |
| Target/Specificity TRIM68 (NP_060543, 181 a.a. ~ 281 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions TRIM68 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
TRIM68 Antibody (monoclonal) (M01) - Related products
TRIM68 Antibody (monoclonal) (M01) - Application data
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Detection limit for recombinant GST tagged TRIM68 is approximately 0.3ng/ml as a capture antibody.
TRIM68 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.
REFERENCES
Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group. Malhotra A, et al. Diabetes Metab Res Rev, 2009 Nov. PMID 19795399.TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells. Miyajima N, et al. Cancer Res, 2008 May 1. PMID 18451177.The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901.From ORFeome to biology: a functional genomics pipeline. Wiemann S, et al. Genome Res, 2004 Oct. PMID 15489336.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
