TROVE2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant TROVE2.
|Application ||WB, E|
|Calculated MW||60671 Da|
|Other Names||60 kDa SS-A/Ro ribonucleoprotein, 60 kDa Ro protein, 60 kDa ribonucleoprotein Ro, RoRNP, Ro 60 kDa autoantigen, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, SS-A, TROVE domain family member 2, TROVE2, RO60, SSA2|
|Target/Specificity||TROVE2 (NP_004591, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||TROVE2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496. Reactivity with dichotomous determinants of Ro 60 stratifies autoantibody responses in lupus and primary Sj?gren's syndrome. Reed JH, et al. Arthritis Rheum, 2010 May. PMID 20131295. Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block. Clancy RM, et al. J Immunol, 2010 Feb 15. PMID 20089705. Ro 60 functions as a receptor for beta(2)-glycoprotein I on apoptotic cells. Reed JH, et al. Arthritis Rheum, 2009 Mar. PMID 19248095. Human Y5 RNA specializes a Ro ribonucleoprotein for 5S ribosomal RNA quality control. Hogg JR, et al. Genes Dev, 2007 Dec 1. PMID 18056422.
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