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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TRPV5 Antibody (monoclonal) (M02)   

TRPV5 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant TRPV5.

  • WB - TRPV5 Antibody (monoclonal) (M02) AT4371a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - TRPV5 Antibody (monoclonal) (M02) AT4371a
    TRPV5 monoclonal antibody (M02), clone 2A6. Western Blot analysis of TRPV5 expression in human kidney.
  • E - TRPV5 Antibody (monoclonal) (M02) AT4371a
    Detection limit for recombinant GST tagged TRPV5 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQA5
Other Accession NM_019841
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2A6
Calculated MW 82551 Da
Additional Information
Gene ID 56302
Other Names Transient receptor potential cation channel subfamily V member 5, TrpV5, Calcium transport protein 2, CaT2, Epithelial calcium channel 1, ECaC, ECaC1, Osm-9-like TRP channel 3, OTRPC3, TRPV5, ECAC1
Target/Specificity TRPV5 (NP_062815, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTRPV5 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.


TRPV-5 mediates a receptor activator of NF-kappaB (RANK) ligand-induced increase in cytosolic Ca2+ in human osteoclasts and down-regulates bone resorption. Chamoux E, et al. J Biol Chem, 2010 Aug 13. PMID 20547482.Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium. Kennedy BG, et al. Mol Vis, 2010 Apr 14. PMID 20405023.High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Yerges LM, et al. J Bone Miner Res, 2009 Dec. PMID 19453261.Parathyroid hormone activates TRPV5 via PKA-dependent phosphorylation. de Groot T, et al. J Am Soc Nephrol, 2009 Aug. PMID 19423690.Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells. Semenova SB, et al. Am J Physiol Cell Physiol, 2009 May. PMID 19295174.

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$ 315.00
Cat# AT4371a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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