TSC22D1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant TSC22D1.
|Application ||WB, IF, E|
|Calculated MW||109677 Da|
|Other Names||TSC22 domain family protein 1, Cerebral protein 2, Regulatory protein TSC-22, TGFB-stimulated clone 22 homolog, Transforming growth factor beta-1-induced transcript 4 protein, TSC22D1, KIAA1994, TGFB1I4, TSC22|
|Target/Specificity||TSC22D1 (AAH00456, 1 a.a. ~ 144 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||TSC22D1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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TSC22D1 encodes a transcription factor and belongs to the large family of early response genes.
A TSC22-like motif defines a novel antiapoptotic protein family. Khoury CM, et al. FEMS Yeast Res, 2008 Jun. PMID 18355271.Interaction between fortilin and transforming growth factor-beta stimulated clone-22 (TSC-22) prevents apoptosis via the destabilization of TSC-22. Lee JH, et al. FEBS Lett, 2008 Apr 9. PMID 18325344.Expression and cellular localization of TSC-22 in normal salivary glands and salivary gland tumors: implications for tumor cell differentiation. Doi Y, et al. Oncol Rep, 2008 Mar. PMID 18288391.Identification of TSC-22 as a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD. Lu Y, et al. Leukemia, 2007 Nov. PMID 17690703.TGF-beta1 and TSC-22 gene polymorphisms and susceptibility to microvascular complications in type 2 diabetes. Buraczynska M, et al. Nephron Physiol, 2007. PMID 17622752.
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