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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TSPAN1 Antibody (monoclonal) (M01)   

TSPAN1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant TSPAN1.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60635
Other Accession NM_005727
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG
Clone Names 5G11
Calculated MW 26301 Da
Additional Information
Gene ID 10103
Other Names Tetraspanin-1, Tspan-1, Tetraspan NET-1, Tetraspanin TM4-C, TSPAN1
Target/Specificity TSPAN1 (NP_005718, 110 a.a. ~ 211 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTSPAN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.


Glycosylation of tetraspanin Tspan-1 at four distinct sites promotes its transition through the endoplasmic reticulum. Scholz CJ, et al. Protein Pept Lett, 2009. PMID 19508227.Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study. Lin X, et al. Diabetologia, 2009 Apr. PMID 19139842.Tspan-1 is a tetraspanin preferentially expressed by mucinous and endometrioid subtypes of human ovarian carcinomas. Scholz CJ, et al. Cancer Lett, 2009 Mar 18. PMID 19017553.Midkine promotes tetraspanin-integrin interaction and induces FAK-Stat1alpha pathway contributing to migration/invasiveness of human head and neck squamous cell carcinoma cells. Huang Y, et al. Biochem Biophys Res Commun, 2008 Dec 12. PMID 18851943.Clinicopathological significance of overexpression of TSPAN1, Ki67 and CD34 in gastric carcinoma. Chen L, et al. Tumori, 2008 Jul-Aug. PMID 18822690.

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$ 315.00
Cat# AT4379a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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