UBE2G2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant UBE2G2.
|Application ||WB, IHC, E|
|Calculated MW||18566 Da|
|Other Names||Ubiquitin-conjugating enzyme E2 G2, Ubiquitin carrier protein G2, Ubiquitin-protein ligase G2, UBE2G2|
|Target/Specificity||UBE2G2 (NP_003329, 1 a.a. ~ 87 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||UBE2G2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
1.Ataxin-3 Deubiquitination Is Coupled to Parkin Ubiquitination via E2 Ubiquitin-conjugating Enzyme.Durcan TM, Kontogiannea M, Bedard N, Wing SS, Fon EA.J Biol Chem. 2012 Jan 2;287(1):531-41. Epub 2011 Nov 11.
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