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UBE2H Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT4437a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
UBE2H Antibody (monoclonal) (M01) - Product info | |
| Application | IF, WB
|
| Primary Accession | P62256 |
| Reactivity | Human |
| Isotype | IgG2a kappa |
| Clone Names | 3C4-1A2 |
| Calculated MW | 20655 Da |
UBE2H Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 7328 | |
| Other Names E220K, UBC8, UBCH, UBCH2ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) | |
| Target/Specificity UBE2H (AAH06277, 1 a.a. ~ 184 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions UBE2H Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
UBE2H Antibody (monoclonal) (M01) - Related products
AP2122b: UBE2H Antibody (C-term)
RI15577: UBE2H predesign siRNA
DC01921: Human UBE2H cDNA Clone
UBE2H Antibody (monoclonal) (M01) - Application data
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Immunofluorescence of monoclonal antibody to UBE2H (AT4437a) on HeLa cell. [antibody concentration 10ug/ml]
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UBE2H monoclonal antibody (M01), clone 3C4-1A2 Western Blot analysis of UBE2H expression in HeLa ( Cat # L013V1 ).
UBE2H Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
REFERENCES
Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1. Lausen J, et al. J Biol Chem, 2010 Feb 19. PMID 20028976.Association study of the ubiquitin conjugating enzyme gene UBE2H in sporadic ALS. Martin I, et al. Amyotroph Lateral Scler, 2009 Oct-Dec. PMID 19922136.A common variant in DRD3 receptor is associated with autism spectrum disorder. de Krom M, et al. Biol Psychiatry, 2009 Apr 1. PMID 19058789.Association study of the ubiquitin conjugating enzyme gene UBE2H in sporadic ALS. Martin I, et al. Amyotroph Lateral Scler, 2008 Oct 14. PMID 18855187.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
