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UBE3A Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant UBE3A.

  • WB - UBE3A Antibody (monoclonal) (M01) AT4445a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - UBE3A Antibody (monoclonal) (M01) AT4445a
    UBE3A monoclonal antibody (M01), clone 2F6 Western Blot analysis of UBE3A expression in Jurkat ( (Cat # AT4445a )
  • IHC - UBE3A Antibody (monoclonal) (M01) AT4445a
    Immunoperoxidase of monoclonal antibody to UBE3A on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml]
  • IF - UBE3A Antibody (monoclonal) (M01) AT4445a
    Immunofluorescence of monoclonal antibody to UBE3A on HeLa cell. [antibody concentration 10 ug/ml]
  • E - UBE3A Antibody (monoclonal) (M01) AT4445a
    Detection limit for recombinant GST tagged UBE3A is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q05086
Other Accession BC009271
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2F6
Calculated MW 100688 Da
Additional Information
Gene ID 7337
Other Names Ubiquitin-protein ligase E3A, 632-, E6AP ubiquitin-protein ligase, Human papillomavirus E6-associated protein, Oncogenic protein-associated protein E6-AP, Renal carcinoma antigen NY-REN-54, UBE3A, E6AP, EPVE6AP, HPVE6A
Target/Specificity UBE3A (AAH09271, 51 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsUBE3A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations ( 0 )


This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.


1.The E6 proteins from multiple beta HPV types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation.Underbrink MP, Howie HL, Bedard KM, Koop JI, Galloway DA.J Virol. 2008 Nov;82(21):10408-17. Epub 2008 Aug 20.

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$ 315.00
Cat# AT4445a
(40 western blots)
Availability: 7-10 days
Bulk Size
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