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UMPS Antibody (monoclonal) (M05)

Mouse monoclonal antibody raised against a partial recombinant UMPS.

  • WB - UMPS Antibody (monoclonal) (M05) AT4467a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - UMPS Antibody (monoclonal) (M05) AT4467a
    Western Blot analysis of UMPS expression in transfected 293T cell line by UMPS monoclonal antibody (M05), clone 2F5.

    Lane 1: UMPS transfected lysate(52.2 KDa).
    Lane 2: Non-transfected lysate.
  • IF - UMPS Antibody (monoclonal) (M05) AT4467a
    Immunofluorescence of monoclonal antibody to UMPS on HeLa cell . [antibody concentration 10 ug/ml]
  • E - UMPS Antibody (monoclonal) (M05) AT4467a
    Detection limit for recombinant GST tagged UMPS is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11172
Other Accession NM_000373
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 2F5
Calculated MW 52222 Da
Additional Information
Gene ID 7372
Other Names Uridine 5'-monophosphate synthase, UMP synthase, Orotate phosphoribosyltransferase, OPRT, OPRTase, Orotidine 5'-phosphate decarboxylase, ODC, OMPdecase, UMPS
Target/Specificity UMPS (NP_000364, 381 a.a. ~ 479 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsUMPS Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.


1.Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study.Koopman M, Venderbosch S, van Tinteren H, Ligtenberg MJ, Nagtegaal I, Van Krieken JH, Punt CJ.Eur J Cancer. 2009 Jul;45(11):1999-2006. Epub 2009 May 18.

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$ 315.00
Cat# AT4467a
(40 western blots)
Availability: 7-10 days
Bulk Size
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