UNC5B Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant UNC5B.
|Application ||WB, E|
|Calculated MW||103638 Da|
|Other Names||Netrin receptor UNC5B, Protein unc-5 homolog 2, Protein unc-5 homolog B, p53-regulated receptor for death and life protein 1, UNC5B, P53RDL1, UNC5H2|
|Target/Specificity||UNC5B (NP_734465, 27 a.a. ~ 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||UNC5B Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
UNC5B belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Characterization and expression of netrin-1 and its receptors UNC5B and DCC in human placenta. Dakouane-Giudicelli M, et al. J Histochem Cytochem, 2010 Jan. PMID 19826074.Role of the netrin system of repellent factors on synovial fibroblasts in rheumatoid arthritis and osteoarthritis. Schubert T, et al. Int J Immunopathol Pharmacol, 2009 Jul-Sep. PMID 19822088.Unc5B associates with LARG to mediate the action of repulsive guidance molecule. Hata K, et al. J Cell Biol, 2009 Mar 9. PMID 19273616.Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. Lesch KP, et al. J Neural Transm, 2008 Nov. PMID 18839057.
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