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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   UPK1B Antibody (monoclonal) (M02)   

UPK1B Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant UPK1B.

  • WB - UPK1B Antibody (monoclonal) (M02) AT4474a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
  • E - UPK1B Antibody (monoclonal) (M02) AT4474a
    Detection limit for recombinant GST tagged UPK1B is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75841
Other Accession NM_006952
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 10
Calculated MW 29643 Da
Additional Information
Gene ID 7348
Other Names Uroplakin-1b, UP1b, Tetraspanin-20, Tspan-20, Uroplakin Ib, UPIb, UPK1B, TSPAN20
Target/Specificity UPK1B (NP_008883, 131 a.a. ~ 228 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsUPK1B Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.


Endometrial biopsy-induced gene modulation: first evidence for the expression of bladder-transmembranal uroplakin Ib in human endometrium. Kalma Y, et al. Fertil Steril, 2009 Apr. PMID 18355812.Uroplakin Ib gene transcription in urothelial tumor cells is regulated by CpG methylation. Cowled P, et al. Neoplasia, 2005 Dec. PMID 16354592.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Methylation of a CpG island within the uroplakin Ib promoter: a possible mechanism for loss of uroplakin Ib expression in bladder carcinoma. Varga AE, et al. Neoplasia, 2004 Mar-Apr. PMID 15140401.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.

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$ 315.00
Cat# AT4474a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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