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USF2 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant USF2.

     
  • IF - USF2 Antibody (monoclonal) (M03) AT4480a
    Immunofluorescence of monoclonal antibody to USF2 on HeLa cell. [antibody concentration 10 ug/ml]
    detail
  • WB - USF2 Antibody (monoclonal) (M03) AT4480a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
    detail
  • WB - USF2 Antibody (monoclonal) (M03) AT4480a
    USF2 monoclonal antibody (M03), clone 6A9. Western Blot analysis of USF2 expression in PC-12 ( (Cat # AT4480a )
    detail
  • WB - USF2 Antibody (monoclonal) (M03) AT4480a
    USF2 monoclonal antibody (M03), clone 6A9. Western Blot analysis of USF2 expression in Hela S3 NE ( (Cat # AT4480a )
    detail
  • WB - USF2 Antibody (monoclonal) (M03) AT4480a
    USF2 monoclonal antibody (M03), clone 6A9. Western Blot analysis of USF2 expression in different cell lines.
    detail
  • E - USF2 Antibody (monoclonal) (M03) AT4480a
    Detection limit for recombinant GST tagged USF2 is approximately 0.03ng/ml as a capture antibody.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession Q15853
Other Accession NM_003367
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 6A9
Calculated MW 36955 Da
Additional Information
Gene ID 7392
Other Names Upstream stimulatory factor 2, Class B basic helix-loop-helix protein 12, bHLHb12, FOS-interacting protein, FIP, Major late transcription factor 2, Upstream transcription factor 2, USF2, BHLHB12
Target/Specificity USF2 (NP_003358, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsUSF2 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
citation

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Background

This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene.

References

Upstream stimulatory factor 2, a novel FoxA1-interacting protein, is involved in prostate-specific gene expression. Sun Q, et al. Mol Endocrinol, 2009 Dec. PMID 19846536.The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors. Landa I, et al. PLoS Genet, 2009 Sep. PMID 19730683.HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells. Wang L, et al. Int J Cancer, 2009 Apr 1. PMID 19089909.Upstream stimulatory factors are involved in the P1 promoter directed transcription of the A beta H-J-J locus. Finotti A, et al. BMC Mol Biol, 2008 Dec 16. PMID 19087304.Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth. Agirre X, et al. Mol Cancer Res, 2008 Dec. PMID 19074828.

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$ 350.00
Cat# AT4480a
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Availability: 7-10 days
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