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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   USP15 Antibody (monoclonal) (M01)   

USP15 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant USP15.

  • WB - USP15 Antibody (monoclonal) (M01) AT4484a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (51.59 KDa) .
  • WB - USP15 Antibody (monoclonal) (M01) AT4484a
    USP15 monoclonal antibody (M01), clone 1C10 Western Blot analysis of USP15 expression in HepG2 ( (Cat # AT4484a )
  • WB - USP15 Antibody (monoclonal) (M01) AT4484a
    Western Blot analysis of USP15 expression in transfected 293T cell line by USP15 monoclonal antibody (M01), clone 1C10.

    Lane 1: USP15 transfected lysate (Predicted MW: 109.3 KDa).
    Lane 2: Non-transfected lysate.
  • IF - USP15 Antibody (monoclonal) (M01) AT4484a
    Immunofluorescence of monoclonal antibody to USP15 on HeLa cell. [antibody concentration 10 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y4E8
Other Accession BC020688
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 1C10
Calculated MW 112419 Da
Additional Information
Gene ID 9958
Other Names Ubiquitin carboxyl-terminal hydrolase 15, Deubiquitinating enzyme 15, Ubiquitin thioesterase 15, Ubiquitin-specific-processing protease 15, Unph-2, Unph4, USP15, KIAA0529
Target/Specificity USP15 (AAH20688, 1 a.a. ~ 235 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsUSP15 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). Also see USP1 (MIM 603478).


1.The Ubiquitin-Specific Protease USP15 Promotes RIG-I–Mediated Antiviral Signaling by Deubiquitylating TRIM25.Pauli EK, Chan YK, Davis ME, Gableske S, Wang MK, Feister KF, Gack MU.Science Signaling 7 (307), ra3.2.The Ubiquitin-Specific Protease USP15 Promotes RIG-I-Mediated Antiviral Signaling by Deubiquitylating TRIM25.Pauli EK, Chan YK, Davis ME, Gableske S, Wang MK, Feister KF, Gack MUSci Signal. 2014 Jan 7;7(307):ra3. doi: 10.1126/scisignal.2004577.3.The Human COP9 Signalosome Protects Ubiquitin-conjugating Enzyme 3 (UBC3/Cdc34) from {beta}-Transducin Repeat-containing Protein ({beta}TrCP)-mediated Degradation.Fernandez-Sanchez ME, Sechet E, Margottin-Goguet F, Rogge L, Bianchi E.J Biol Chem. 2010 Jun 4;285(23):17390-7. Epub 2010 Apr 8.4.COP9 Signalosome Interacts ATP-dependently with p97/Valosin-containing Protein (VCP) and Controls the Ubiquitination Status of Proteins Bound to p97/VCP.Cayli S, Klug J, Chapiro J, Frohlich S, Krasteva G, Orel L, Meinhardt A.J Biol Chem. 2009 Dec 11;284(50):34944-53. Epub 2009 Oct 13.5.USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis.Xu M, Takanashi M, Oikawa K, Tanaka M, Nishi H, Isaka K, Kudo M, Kuroda M.Biochem Biophys Res Commun. 2009 Oct 16;388(2):366-71. Epub 2009 Aug 8.6.The Ubiquitin Specific Peptidase USP15 Regulates Human Papilloma Virus 16 E6 Protein Stability.Vos RM, Altreuter J, White EA, Howley PM.J Virol. 2009 Sep;83(17):8885-92. Epub 2009 Jun 24.7.The COP9/signalosome increases the efficiency of pVHL ubiquitin ligase-mediated hypoxia inducible factor-alpha ubiquitination.Miyauchi Y, Kato M, Tokunaga F, Iwai K.J Biol Chem. 2008 Jun 13;283(24):16622-16631. Epub 2008 Apr 18.8.CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha.Schweitzer K, Bozko PM, Dubiel W, Naumann M.EMBO J. 2007 Mar 21;26(6):1532-41. Epub 2007 Feb 22.

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$ 315.00
Cat# AT4484a
Availability: 7-10 days
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