VAPA Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full-length recombinant VAPA.
|Application ||WB, IF|
|Calculated MW||27893 Da|
|Other Names||Vesicle-associated membrane protein-associated protein A, VAMP-A, VAMP-associated protein A, VAP-A, 33 kDa VAMP-associated protein, VAP-33, VAPA, VAP33|
|Target/Specificity||VAPA (AAH02992, 1 a.a. ~ 242 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||VAPA Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies. Furuita K, et al. J Biol Chem, 2010 Apr 23. PMID 20178991.The glycolipid transfer protein interacts with the vesicle-associated membrane protein-associated protein VAP-A. Tuuf J, et al. Biochem Biophys Res Commun, 2009 Oct 16. PMID 19665998.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein. Saita S, et al. J Biol Chem, 2009 May 15. PMID 19289470.FFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregation. Prosser DC, et al. J Cell Sci, 2008 Sep 15. PMID 18713837.
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