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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   VCL Antibody (monoclonal) (M01)   

VCL Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant VCL.

  • WB - VCL Antibody (monoclonal) (M01) AT4505a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (143 KDa) .
  • WB - VCL Antibody (monoclonal) (M01) AT4505a
    VCL monoclonal antibody (M01), clone 2C6-1B5 Western Blot analysis of VCL expression in Hela ( (Cat # AT4505a )
  • IF - VCL Antibody (monoclonal) (M01) AT4505a
    Immunofluorescence of monoclonal antibody to VCL on HeLa cell. [antibody concentration 10 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P18206
Other Accession BC039174
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 2C6-1B5
Calculated MW 123799 Da
Additional Information
Gene ID 7414
Other Names Vinculin, Metavinculin, MV, VCL
Target/Specificity VCL (AAH39174.1, 1 a.a. ~ 1066 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsVCL Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.


1.Ascorbylperoxide contaminating parenteral nutrition perturbs the lipid metabolism in newborn guinea pig.Maghdessian R, Cote F, Rouleau T, Ouadda AB, Levy E, Lavoie JC.J Pharmacol Exp Ther. 2010 Apr 7. [Epub ahead of print]

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$ 315.00
Cat# AT4505a
(40 western blots)
Availability: 7-10 days
Bulk Size
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