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VIM Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT4513a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
VIM Antibody (monoclonal) (M01) - Product info | |
| Application | IF, WB
|
| Primary Accession | P08670 |
| Reactivity | Human |
| Isotype | IgG2a Kappa |
| Clone Names | 3000000000 |
| Calculated MW | 53652 Da |
VIM Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 7431 | |
| Other Names FLJ36605vimentin | |
| Target/Specificity VIM (AAH30573, 41 a.a. ~ 141 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions VIM Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
VIM Antibody (monoclonal) (M01) - Related products
AP2739a: Vimentin Antibody (S82)
AP2739b: Vimentin Antibody (C-term)
AP2739c: Vimentin Antibody (Center)
AP3546a: Phospho-Vimentin-S82 Antibody
LY10969a: VIM Over-expression Lysate
BP2739a: Vimentin Antibody (S82) Blocking Peptide
BP2739b: Vimentin Antibody (C-term) Blocking Peptide
BP2739c: Vimentin Antibody (Center) Blocking Peptide
VIM Antibody (monoclonal) (M01) - Application data
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Immunofluorescence of monoclonal antibody to VIM (AT4513a) on HeLa cell . [antibody concentration 40 ug/ml]
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VIM monoclonal antibody (M01), clone 3E9 Western Blot analysis of VIM expression in HeLa ( Cat # L013V1 ).
VIM Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
REFERENCES
Aberrant expression of vimentin correlates with dedifferentiation and poor prognosis in patients with intrahepatic cholangiocarcinoma. Korita PV, et al. Anticancer Res, 2010 Jun. PMID 20651380.Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 May 14. PMID 20471030.Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064.Divalent cations crosslink vimentin intermediate filament tail domains to regulate network mechanics. Lin YC, et al. J Mol Biol, 2010 Jun 18. PMID 20447406.Diagnostic value and implications of vimentin expression in normal, reactive and neoplastic endocervical epithelium. Stewart CJ, et al. Pathology, 2010 Apr. PMID 20350213.
