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VPREB3 Antibody (monoclonal) (M08)

Mouse monoclonal antibody raised against a partial recombinant VPREB3.

  • WB - VPREB3 Antibody (monoclonal) (M08) AT4517a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - VPREB3 Antibody (monoclonal) (M08) AT4517a
    Western Blot analysis of VPREB3 expression in transfected 293T cell line by VPREB3 monoclonal antibody (M08), clone 4H8.

    Lane 1: VPREB3 transfected lysate(13.7 KDa).
    Lane 2: Non-transfected lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UKI3
Other Accession NM_013378
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4H8
Calculated MW 13710 Da
Additional Information
Gene ID 29802
Other Names Pre-B lymphocyte protein 3, N27C7-2, Protein VPreB3, VPREB3
Target/Specificity VPREB3 (NP_037510, 24 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsVPREB3 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is the human homolog of the mouse VpreB3 (8HS20) protein, and is specifically expressed in cell lines representative of all stages of B-cell differentiation. It is also related to VPREB1 and other members of the immunoglobulin supergene family. This protein associates with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. The precise function of the protein is not known, but it may contribute to mu chain transport in pre-B cells.


Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.Assembly of the kappa preB receptor requires a V kappa-like protein encoded by a germline transcript. Rangel R, et al. J Biol Chem, 2005 May 6. PMID 15757909.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.A genome annotation-driven approach to cloning the human ORFeome. Collins JE, et al. Genome Biol, 2004. PMID 15461802.Binding of free immunoglobulin light chains to VpreB3 inhibits their maturation and secretion in chicken B cells. Rosnet O, et al. J Biol Chem, 2004 Mar 12. PMID 14670953.

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$ 315.00
Cat# AT4517a
(40 western blots)
Availability: 7-10 days
Bulk Size
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